Our team’s collective experience over decades in the industry allows us to meet an urgent need for quality protein production in both the drug development and research arenas. We understand this need because we have been there ourselves, searching for qualified services and facilities.
Our handpicked team of experts has come together to provide protein production services with the quality and grade required for your projects.
Over 30 years experience in ADC and protein production and development. Expertise in the drug development process from laboratory to clinic. Check out our scientific publications.
Dr. Woo has 28 years of experience in molecular biology research and targeted drug
development. This experience includes the operation of a Contract Manufacturing Facility for production of biological drugs. As a Principal Investigator, he was successfully funded by 18 grants/contracts that resulted in the translation of scientific discoveries into 11 investigational new drug (IND) applications. Six INDs were approved for testing drug candidates in Phase I clinical trials. One of these candidates was FDA-approved as a prescription medicine. Dr. Woo has been instrumental in assisting Advanced Targeting Systems to set up a new GMP production company, Advanced Protein Productions.
Denise has worked on the administrative side of scientific entities for over 40 years. Her career began in the laboratories of Dr. Roger Guillemin, M.D., Ph.D., Nobel Prize winner. She moved on to become the Project Manager at The Whittier Institute for Diabetes and Endocrinology, Department of Molecular and Cellular Growth Biology, where she gained valuable experience in the grant application and management processes. From 1992-1998, Denise was Administration Manager for the Invitrogen Corporation, where she participated in the path from private company to an IPO. In her role as President and Founder of Advanced Targeting Systems, Denise envisioned the necessity of having a company that could produce GMP-grade commercial drugs. Advanced Protein Production was launched to meet that important need to progress well- characterized research reagents into the pharmaceutical arena.
Soo has expertise in Drug Manufacturing R&D fields including Early-Stage Drug Development (gene construction, protein expression, in vitro studies), Process Development & GMP manufacturing (fermentation, purification), Quality Control (release tests, stability tests, functional assays), Animal Studies (rat PK study, mouse xenograft efficacy study), and Clinical Pharmacology (development and performance of pharmacokinetic assays for Phase I & II clinical trials).
Dr. Lappi is a global expert on the use of the ribosome-inactivating protein, Saporin. As a founder in 1994 of the targeted toxin company, Advanced Targeting Systems, he brings decades of experience in chemical conjugations and cell-specific targeting techniques. Dr. Lappi holds a bachelor’s degree in biology from the University of California, San Diego, and a Ph.D. in applied biochemistry from the University of Bologna, Italy. His first ADC, 192-IgG-SAP, was the cornerstone for founding Advanced Targeting Systems and is the basis for a reliable validated model of Alzheimer’s Disease.
Leonardo has 20 years of experience in the development and manufacturing of research reagents focusing on antibody/peptide conjugates, with expertise in the ribosome-inactivating protein saporin as the payload. Leonardo’s expertise in customizing conjugations utilizes size, structure, and chemistry to produce efficient and stable protein conjugates. His experience in designing and executing cell-based assays produces the data needed to provide a solid Certificate of Analysis for each service.
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We are U.S. based facility with over 30 years of experience in Drug-Antibody-Conjugates.
Our team of experts can take on your project in any phase, whether it's during process development, before GMP, or when you're ready for the final phases of product production.
Convenient scheduling and availability to serve you in your next project.
Direct experience and success with 18 contracts, 11 INDs, 6 Phase 1 clinical trials, and 1 approved medicine. We can take your project from start to finish with excellence.
All processing for stem cell banking as well as therapeutic manufacturing takes place in ISO 7 and 8 cleanrooms designed, certified and monitored in accordance with ISO 14644-1 & 14644-2 standards. All procedures are performed in compliance with cGMP/cGLP regulations. To ensure consistency, we have established a quality management system in accordance with ISO 9001:2015. All of the products we make are proudly made in the USA for exclusive use in the USA.
