Exceptional efficiency and uncompromising quality to Advance your Protein Production
Advanced Protein Production (APP) is a Contract Development and Manufacturing Organization, CDMO. With over a decade of expertise in establishing and operating GMP-compliant facilities, the director of Advanced Protein Production (APP) possesses unparalleled knowledge and experience in leading a state-of-the-art facility designed for protein expression and purification. By focusing on protein methodology, APP has the capability to produce large volumes of proteins for both research and clinical applications. In addition, our conjugation facilities enable us to offer Antibody-Drug-Conjugates (ADCs) and other protein conjugates, prepared by a team with decades of experience in chemistry, using the impeccable GMP materials that we produce.
For emerging biotechnology firms that are pioneering innovative protein-based therapies, the availability of a readily accessible GMP production facility is indispensable. APP’s presence optimizes the drug development process unlike any other, providing a streamlined and efficient pathway for bringing these novel therapies to market.
Latest Technology & Facility
Advanced Protein Production specializes in providing contract manufacturing services to academic research institutions and biotechnology/pharmaceutical companies involved in preclinical and clinical development. Our comprehensive package includes process development, scaled manufacturing, purification, conjugation, QC testing, and CMC (Chemistry, Manufacturing, and Controls) documentation. Our team is dedicated to tailoring programs to meet the specific guidelines and regulatory requirements of each client.
Cutting Edge Facility & Equipment
Our GMP manufacturing facility has flexible space for fermentation, purification, as well as protein conjugations and QC testing. We utilize different host systems, such as yeasts, Escherichia coli, and mammalian cells to produce clinical grade molecules. These molecules serve as potential drug candidates or intermediates for preclinical studies and clinical trials. As part of the process, we create and qualify master cell banks and working cell banks for the production cell lines.
NBS 150L BioFlo Fermentor
NBS 40L Fermentor
Wave Bioreactor Mixer Systems
AKTA Pilot GE FPLC purification system
AKTA Purifer
Hirayama Autoclave
Large capacity centrifuges
Bioprocess columns
Laminar flow hoods
Our Expertise
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Protein Expression & Production
Bacterial (E. coli)
Yeast (Pichia pastoris)
Mammalian (CHO and HEK293)
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Protein Conjugations
Chemical - Cleavable linker
Chemical - Non-cleavable linker
Fusion Protein
DAR Evaluations
Target - Peptide, Antibody, Aptamer, Other